V4505
 |    |  |
 | Immunofluorescence Double labeling of an isolated smooth muscle cell (chicken gizzard) with Monoclonal Anti-Vinculin, clone no. VIN-11-5, (Cat. No. V4505) (green) and Anti-α-Actinin (red). |
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V4505
Sigma
Monoclonal Anti-Vinculin antibody produced in mouse
clone VIN-11-5, ascites fluid
| Synonym: | Anti-VCL |
| MDL number: | MFCD00162905 |
Description
| Immunogen | smooth muscle vinculin from chicken gizzard. |
| Specificity | The antibody reacts best with cultured chicken fibroblasts. Labeling also may be obtained with bovine, human, or mouse cells. |
Properties
| antibody form | ascites fluid |
| clone | VIN-11-5 (monoclonal) |
| mol wt | antigen mol wt 116 kDa |
| contains | 15 mM sodium azide |
| species reactivity | bovine, mouse, chicken, human |
| application(s) | immunoblotting: suitable |
| indirect immunofluorescence: 1:50 using cultured chicken fibroblasts | |
| microarray: suitable | |
| isotype | IgG1 |
| Gene Information | human ... VCL(7414) |
| mouse ... Vcl(22330) | |
| shipped in | dry ice |
| storage temp. | −20°C |
Safety
| WGK Germany | 3 |
Related Products
References
| reference | Volberg, T., et al., Changes in membrane-microfilament interaction in intercellular adherens junctions upon removal of extracellular Ca2+ ions. J. Cell Biol. 102, 1832, (1986) Abstract |
| Hall, L., Role of Actin Polymerization and Adhesion to Extracellular Matrix in Rac- and Rho-induced Cytoskeletal Reorganization J. Cell Biol. 138, 913-926, (1997) Abstract | |
| Maggs, A.M., et al., The Transitional Junction: A New Functional Subcellular Domain at the Intercalated Disc Mol. Biol. Cell 17, 2091-2100, (2006) Abstract | |
| Aplin, A.E., et al., B-RAF Regulation of Rnd3 Participates in Actin Cytoskeletal and Focal Adhesion Organization Mol. Biol. Cell 19, 498-508, (2008) Abstract |
